SCOPE-HN: A Segmentation-based Collection of OroPharyngeal Structures Using Flexible Endoscopy for Head and Neck Cancers

Nikita Bedi1Orcid, Anita Rau2Orcid, Alberto Paderno3Orcid, Hlu Vang1Orcid, Yoon Kyoung So1Orcid, F.~Christopher Holsinger1Orcid
1: Division of Head & Neck Surgery, Department of Otolaryngology, Stanford University, 2: Department of Biomedical Data Science, Stanford University, 3: Department of Otolaryngology–Head and Neck Surgery, Humanitas Research Hospital
Publication date: 2025/12/31
https://doi.org/10.59275/j.melba.2025-51gc
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Abstract

Oropharyngeal cancer (OPC) is one of the few cancers with a rising incidence, driven primarily by increasing rates of human papillomavirus (HPV)-associated disease. Early detection and accurate delineation of OPC are critical for diagnosis, treatment planning and improving outcomes but remain challenging due to anatomical complexity and variability in clinical expertise. We present the SCOPE-HN dataset, a curated collection of annotated endoscopic images from 106 patients with histologically confirmed OPC, collected at Stanford between 2015 and 2023. The dataset consists of 942 RGB images extracted from diagnostic nasopharyngolaryngoscopy videos, with pixel-level annotations performed by expert Head and Neck surgeons. Annotations include 12 semantic classes representing tumor, normal anatomical structures, and common endoscopic artifacts. The SCOPE-HN dataset is publicly available at scope-hn.stanford.edu or bit.ly/SCOPE-HN under the Stanford University Dataset Research Use Agreement license.

Keywords

Oropharyngeal cancer · endoscopy · segmentation · dataset · annotation · machine learning · UADT

Bibtex @article{melba:2025:047:bedi, title = "SCOPE-HN: A Segmentation-based Collection of OroPharyngeal Structures Using Flexible Endoscopy for Head and Neck Cancers", author = "Bedi, Nikita and Rau, Anita and Paderno, Alberto and Vang, Hlu and So, Yoon Kyoung and Holsinger, F.\textasciitilde Christopher", journal = "Machine Learning for Biomedical Imaging", volume = "3", issue = "Special Issue on Open Data at MICCAI 2024–2025", year = "2025", pages = "913--918", issn = "2766-905X", doi = "https://doi.org/10.59275/j.melba.2025-51gc", url = "https://melba-journal.org/2025:047" }
RISTY - JOUR AU - Bedi, Nikita AU - Rau, Anita AU - Paderno, Alberto AU - Vang, Hlu AU - So, Yoon Kyoung AU - Holsinger, F.~Christopher PY - 2025 TI - SCOPE-HN: A Segmentation-based Collection of OroPharyngeal Structures Using Flexible Endoscopy for Head and Neck Cancers T2 - Machine Learning for Biomedical Imaging VL - 3 IS - Special Issue on Open Data at MICCAI 2024–2025 SP - 913 EP - 918 SN - 2766-905X DO - https://doi.org/10.59275/j.melba.2025-51gc UR - https://melba-journal.org/2025:047 ER -

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